Phytochemical Constituents and Anticogulant Activities of Trigonella Foenum Graecum L. and Cinnamomum Cassia L. Extracts

Abstract

Medicinal plants have been used for treatment of human ailments since ancient times. New alternative anticoagulant molecules can be obtained from plants which are rich in polyphenols and flavonoids. This study was designed to evaluate phytochemical constituents and the anticoagulant effect of T. foenum graecum L. and C. cassia L. ethanolic extracts. The quantitative analysis by the colorimetric method showed that ethanolic extracts of these species were found to be rich in bioactive molecules such as polyphenols, alkaloids, concentrated tannins, mucilage, flavonoids, saponosides, amino acids, cardiac glycosides and anthraquinones that can be used as phytomedicine for various diseases. The anticoagulant activity of ethanolic extracts of these species was also evaluated in vitro using the Quick time test (TQ). The results of the analysis of variance showed that the two extracts had a very highly significant effect on the rate of Quick time. It appears from the results found during the evaluation of the in vitro anticoagulant activity of various extracts of that species should be prescribed with care to patients on anticoagulant therapy.