A Study on The Phytochemical Profile and Therapeutic Potential of Nyctanthes Arbortristis Linn.

Abstract

Nyctanthes arbortristis Linn., commonly known as Night Jasmine, is a plant of significant medicinal value, widely utilized in traditional medicine for its therapeutic properties. This study aimed to identify and quantify the phytochemical constituents of Nyctanthes arbortristis to understand the compounds responsible for its health benefits. Leaf extracts were prepared using aqueous, methanol-aqueous, and acetone-aqueous solvents, followed by qualitative and quantitative phytochemical assays to investigate the presence of secondary metabolites. The qualitative analysis revealed the presence of tannins, terpenoids, saponins, flavonoids, phenolic compounds, reducing sugars, steroids, alkaloids, and glycosides. Quantitative analysis showed that the ethanolic extract of the leaves contained 103.63 mg QE/g of flavonoids and 17.73 mg GAE/g of phenolic compounds. The DPPH radical scavenging activity demonstrated significant antioxidant properties, with the methanol extract showing the highest activity at 32.67%. These findings underscore the medicinal potential of Nyctanthes arbortristis, attributed to its rich phytochemical composition and notable antioxidant activity. The presence of various bioactive compounds supports its traditional use in treating viral infections, diabetes, and other ailments. The high levels of flavonoids and phenolic compounds particularly highlight its potential in combating oxidative stress-related conditions. In conclusion, Nyctanthes arbortristis Linn. stands out as a valuable medicinal plant with a wide range of therapeutic benefits. The study validates its traditional uses and suggests further research to isolate and characterize specific bioactive compounds for potential pharmaceutical applications. This could lead to the development of new, effective treatments derived from this traditional medicinal plant.