The phytochemical profiling of Aloe vera through GC-MS and compounds activity validation at NCBI for industrial value addition of the plant

Abstract

The Aloe vera commonly known as Gwarpatha or Ghrit Kumari is considered as a universal panacea. It is a gifted plant for the health, beauty, medicinal and skincare industry. However, considering the multiple uses of it in other sectors also, it needed to be explored further for other than known industrial and medicinal values. The present study highlights the additional industrial and medicinal properties of the plant. It includes preliminary phytochemicals screening, GC-MS analysis of a Methanolic Extract of Aloe vera (MEAV) leaves and finding out the compounds activities at the international compounds databases of NCBI like PubChem, Drug Bank etc. Out of 200 compounds detected through GC-MS, mainly 46 compounds falling in major peak areas were further explored at the compounds databases. Accordingly, some key phytocompounds such as α-D Glucose, Lactose, Maltotriose, Citronellyl Butyrate, Phytol, Myristic Acid, Capric Acid, Heptadecanoic Acid etc. depicted the important industrial activities like sweet modulator of food stuff, diluents/sweetener for dairy, alcohol, soft drinks, health, beauty, confectionary and pharmaceutical industry; moisturizing and fragrance agent in cream, shampoo, soap, perfumed products; emulsifier, texture enhancer; agent for the lubricants, greases, dyes, plastics, detergent and biodiesel etc. Other than them, several phytocompounds showing medicinal properties like anti-cancer, anti-inflammatory, antioxidant, anti-hypertensive, anti-fungal, anti-bacterial, immunity booster, therapeutic agents for Rheumatoid Arthritis, acute respiratory distress syndrome, Asthma, Cardiovascular Disease, Cancer, Osteoporosis, Insomnia, etc. were also identified in the plant. Consequently, Aloe vera with its great industrial values can be a good source of raw material for several other industries like food, beverage, cosmetic, detergent, soaps, biodiesel pharmaceutical and may be considered for the sustainable aloe-cultivation as alternative cash crop in drought prone area like Bundelkhand region.