Predictive factors of intracytoplasmic injection of spermatozoa failures and abortions in medically assisted procreation in eastern Algeria

Abstract

Context and objective: Infertility is a relatively common pathology in Algeria. The causes are multiple and often remain undetermined, as a result the ma-jority of couples turn to assisted reproduction. The aim of this study was to highlight the different risk factors that cause failures and / or abortions after an intra cytoplasmic sperm injection (ICSI) attempt. Materials and Methods: This was a descriptive retrospective study, involving a sample of 90 patients who attempted ICSI. Using an interrogation, the epidemiological, clinical and paraclinical parameters were recorded. Results: Our results showed that 78% of women had failures, 11% had miscarriages. Age was shown to be a deci-sive factor in the occurrence of miscarriages (p <0.05). Stress is positively correlated with the occurrence of spontaneous miscarriages (p <0.05). Diet also plays a big role in the success of ICSI, especially snacks which significant-ly influence the occurrence of miscarriage (p <0.05). The study found a high rate of failures and abortions in overweight (83%) and obese (77%) patients. Treatment of ovarian stimulation is much higher in obese compared to nor-mal overweight (p <0.05). Pregnancies in women of normal weight signifi-cantly exceeded other categories (p <0.05). Smoking in these two active or passive forms has a negative influence on the sperm quality, as well as the behavior of the fetus (p≤0.05). Conclusion: The results found are testimony to the failures and resulting abortions after ICSI.