Comparative study of the antioxidant and antibacterial activities of the essential oil and methanolic extract of cultivated sage from Mascara region (North West of Algeria) indicates a strong antioxidant activities and an important antibacterial action wi

Abstract

The plant world is an excellent source of active principles, which confers its important activity. In Algeria, a large number of aromatic and medicinal plants grow spontaneously, common sage (Salvia officinalis) is a popular culinary and medicinal herb. These natural products and their active principles are sources for new drug discovery and treatment of diseases. To this end, the interest of this work is the valorization of a medicinal plant (Salvia officinalis) growing spontaneously in the region of Mascara by the study of antioxidant and antibacterial activities of the methanolic extracts and also essential oils of sage. The essential oil was isolated from aerial part of S. officinalis by hydrodistillation. The results obtained showed that the species studied (S. officinalis) was very rich in volatile substances with a yield of the order of1.19%. The antioxidant activity showed a good efficiency of the methanolicextract with respect to the essential oil with IC50s of 0.778 mg / ml and27.929 mg / ml respectively. In general, the essential oil of S. officinalis hasan interesting antibacterial power against all studied germs. These resultsare promising and provide scientific validation of the massive use of this species.