Alterations in the biochemical parameters and the spermatic function generated by obesity in rats

Authors

  • Zahira Abbes Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Demmouche A. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Menadi N. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Mai A. H. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Bahri M. R. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Morsli Z. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Bouazza S. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Ferrag D. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Bekhedda H. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Khalloua Z. C. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Demmouche K. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Zouba M. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria
  • Sebti B. Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

DOI:

https://doi.org/10.38150/sajeb.8(5).p193-201

Abstract

The aim of the present study was to assess the effects of a hyperlipidic diet set before puberty in male Wistar rats’ gonadal weights and testicular func-tions. Males rats were used for the study, they were randomly distributed into 2 groups: Control Group (CG: standard diet (normolipidemic) and the second: Intervention Group (IG: hyperlipidemic diet), after 7 days of experi-mentation, 3 rats were sacrificed per week, blood samples were collected and level of HDL, LDL and triglyceride were analyzed. A significant reduction (p<0.05) in testicular weight in the control group was observed compared with the hyperlipidic diet group, triglyceride levels showed a consistent change over the weeks of the study, HDL levels showed a consistent change during the 5 weeks of the study, Photomicraphie of the testicles of Wistar rats in the hyperlipid diet group for the first week showed Sertoli cell hyper-plasia ,during the second week microscopic examination showed significant testicular hypertrophy the microscopic examination during the fifth week showed hyperplasia of the seminal vesicle characterized by an increase in the number of glandular epithelial cells. The proliferating epithelium may form papillary structures with supporting stroma and with extension into the glandular lumen and total absence of sperm cells. Obesity is associated with many metabolic abnormalities. It has been found that these metabolic ab-normalities induce disorders of spermatogenesis. Our results show that the hyperlipidic diet affects the gonads significantly with hypertrophic testes, the presence of hyperplastic seminiferous tubes, as well as a fine basement membrane.

Author Biographies

Zahira Abbes, Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Demmouche A., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Menadi N., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Mai A. H., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Bahri M. R., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Morsli Z., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Bouazza S., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Ferrag D., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Bekhedda H., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Khalloua Z. C., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Demmouche K., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Zouba M., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Sebti B., Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life Djillali Liabes University. Sidi Bel Abbes. Algeria

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Published

2019-05-09

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Research Articles